Publications

Period: 2025-2026 Return to academic research

1. Delgado-SanMartin, J.A., Errington, N., Keles, M., Schuetz, N., Johnson, A., Gupta, V., Hershman, S., Toshner, M., Wilkins, M.R., Kiely, D.G., Thompson, R., Ashley, E., Wang, D. and Lawrie, A. (2026). Assessing the feasibility of using smartphone data to detect pulmonary arterial hypertension. NPJ Cardiovascular Health.https://doi.org/10.1038/s44325-026-00114-9

Conducted all analyses and led manuscript

2. Delgado-SanMartin, J.A., Gupta, V., McDonough, H.E., Ong, S.J., McDermott, C.J. and Wang, D. (2026). Anticipating gastrostomy intervention in amyotrophic lateral sclerosis: a multi-cohort longitudinal trajectory and survival analysis. Under review at JMIR Medical Informatics - preprint

Conducted all analyses and led manuscript

3. Zhang, H., Lee, Y., Lawrie, A., Wang, D., Delgado-SanMartin, J. (2027). Finding the best time & duration to wear a smartwatch according to science. NPJ Digital Medicine. In preparation.

Leading publication, building digital twin

4. Lee, R., Rothwell, D., Smith, N., Chow, S., Delgado-SanMartin, J., Mistry, H., …, Lorigan, P. Use of circulating tumour DNA to prospectively guide a switch from targeted to immune therapy in BRAF mutant advanced melanoma: the randomised phase II CAcTUS trial - Nature Comms (2026). https://doi.org/10.1038/s41467-026-72735-8

Conducted all analyses

5. Schuetz, N., Bai, Y., Delgado-SanMartin, J.A., Pan, L., Paruchuri, A., Nerisse, F., Lawrie, A. and Ashley, E., Zhang, K. (2026). OpenMHC: Accelerating the Science of Wearable Foundation Models. Under review NeurIPS - preprint

Conducted part of the analyses

6. Said, M.M., de Mooij, R.B., Jiao, D., Delgado-SanMartin, J.A., Rothman, A.M.K., Villar, S., Roussakis, A.A., Aman, J., Mathôt, R.A.A., Swart, E.L., Wilkins, M.R. and Bartelink, I.H. (2026). Adaptive imatinib regimens can mitigate cumulative toxicity while sustaining hemodynamic benefit: a model-based simulation of the PIPAH trial in pulmonary arterial hypertension. Accepted British Journal of Clinical Pharmacology.

Conducted part of the analyses

7. Kim, D.S., Schmiedmayer, P., Johnson, A., Schuetz, N., Kollmer, L., Goldschmidt, P., Delgado-SanMartin, J.A., Zhang, K.W., Mantena, S., Tolas, A., Montalvo, S., Ramirez-Posada, M., O’Sullivan, J.W., Oppezzo, M., King, A.C., Rodriguez, F., Ashley, E.A. and Lawrie, A. (2026). Design and rationale of the My Heart Counts cardiovascular health study: a large-scale, fully digital biobank, and randomized trial of large language model-driven coaching of physical activity. American Journal of Preventive Cardiology. https://doi.org/10.1016/j.ajpc.2026.101565

Implemented ETLs, DevOps/MLOps, backend architecture, and data management strategy and ML

8. Mantena, S., Johnson, A., Schuetz, N., Tolas, A., Montalvo, S., Delgado-SanMartin, J.A., Ramirez-Posada, M., Oppezzo, M., King, A.C., Schmiedmayer, P., Lawrie, A., Rodriguez, F., Ashley, E.A. and Kim, D.S. (2026). Grounding Language Models in Behavioral Science to Scale Physical Activity Interventions for Hispanic/Latinx Populations. Under review at JMIR.

Advised and reviewed analyses & language 

9. Masood, M., Pan, H., Delgado-SanMartin, J.A., Ong, S.J., Zhang, X., Thompson, R., Lawrie, A. and Wang, D. (2026). Pre-diagnostic comorbidity pathways are associated with the timing of pulmonary hypertension outcomes: a case control study. Accepted BMC Pulmonary Medicine

Conducted part of the analyses

10. Rothman AMK,… Delgado-SanMartin JA, … Wilkins MR. Positioning Imatinib for Pulmonary Arterial Hypertension: A Dose-Finding Phase 2 Study. Am J Respir Crit Care Med. 2025 Jun;211(6):1018-1027. doi: 10.1164/rccm.202410-1929OC.

Conducted part of the analyses

11. Hong, P.,... Delgado-SanMartin, J, Wang, D. Genetic liability to metabolic dysfunction modelled in early adulthood predicts cardiometabolic risk across the life course in Asian populations. (2026) Under review in NPJ Genetic Medicine

Advised and reviewed analyses

12. Pham, T., Ghafoor, M., Delgado-SanMartin, J.,Chiong J., Khoo, S., Wang D., Siccardi, M. PIPK-Net: Physiology-Informed Graph Neural Network for the Multitask Prediction of Systemic Pharmacokinetic Properties from Oral Drugs (2026) Under review in CPT: Pharmacometrics & Systems Pharmacology

Original idea. Advised and reviewed analyses

13. Yu, J., Chen, Y., Delgado-SanMartin, J.A., Wang, D., Pan, H. and Zhou, D. (2026). Structured Transfer Learning for Survival Risk Stratification in Data-Sparse Clinical Cohorts. Sent to Journal of Clinical Epidemiology.

Advised and reviewed analyses

14. Hong, P., Delgado-SanMartin, J.A., Wang, D. (2026). Biological Age estimation using LLMs in prenatal and postnatal Asian women. In preparation.

Conducted analyses

2019-2020 During Industrial experience

15. Yates J.W.T., Byrne, H.,... Delgado-SanMartin, J., Vicini, P. Opportunities for Quantitative Translational Modeling in Oncology. ASCPT (2020)  https://doi.org/10.1002/cpt.1963  

Provided perspective from tumour micro-environment.

16. Delgado-SanMartin J, Ehrhardt B, Paczkowski M, Hackett S, Smith A, et al. (2019) An innovative non-invasive technique for subcutaneous tumour measurements. PLOS ONE 14(10): e0216690. https://doi.org/10.1371/journal.pone.0216690

Led the publication, coordinated across centres and performed most of the analysis.

2013-2017 During PhD & MEng

17. Delgado-SanMartin, J.A., Hare, J.I., Davies, E.J. et al. Multiscalar cellular automaton simulates in-vivo tumour-stroma patterns calibrated from in-vitro assay data. BMC Med Inform Decis Mak 17, 70 (2017). https://doi.org/10.1186/s12911-017-0461-1

Led and came up with the idea, performed all analyses.

18. Davies, E. J. … Delgado-SanMartin, J, …et al. Capturing complex tumour biology in vitro: histological and molecular characterisation of precision cut slices. Nature Scientific Reports. 5, 17187; doi: 10.1038/srep17187 (2015).

Contributed on the image analysis of the ex-vivo PDX samples.

19. Delgado-SanMartin JA, Hare JI, de Moura APS, Yates JWT (2015) Oxygen-Driven Tumour Growth Model: A Pathology-Relevant Mathematical Approach. PLOS Computational Biology 11(10): e1004550. https://doi.org/10.1371/journal.pcbi.1004550

Led and came up with the idea, performed all analyses.

20. Juan A. Delgado San Martin, Jennifer I. Hare, James W.T. Yates, Simon T. Barry. Tumour stromal morphology impacts nanomedicine cytotoxicity in patient-derived xenografts,Nanomedicine: Nanotechnology, Biology and Medicine,Volume 11, Issue 5, (2015),Pages 1247-1252,ISSN 1549-9634, https://doi.org/10.1016/j.nano.2015.02.007.

Led and came up with the phenotypes, performed all analyses.

21. Delgado San Martin J, Worthington P, Yates J. Non-invasive 3D time-of-flight imaging technique for tumour volume assessment in subcutaneous models. Laboratory Animals. (2015);49(2):168-171. doi:10.1177/0023677214562653

Led and came up with the idea, performed all analyses.

22. Juan Antonio Delgado San Martín, Mariano Nicolás Cruz Bournazou, Peter Neubauer, Tilman Barz,Mixed integer optimal control of an intermittently aerated sequencing batch reactor for wastewater treatment, Computers & Chemical Engineering, Volume 71, (2014), Pages 298-306, ISSN 0098-1354, doi: https://doi.org/10.1016/j.compchemeng.2014.09.004.

Led and came up with the idea, performed all analyses.

Supported PK modelling and visualisations

Non-academic publications

23. https://creativepool.com/wunderman/projects/unseen-stats-for-bt-sport (2021)